Open Access3‐Deoxy‐2‐octulosonic Acid 5‐Phosphate: a Component of the Endotoxin of Bordetella pertussis
Author(s) -
CHABY Richard,
SZABÓ Ladislas
Publication year - 1975
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1975.tb02452.x
Subject(s) - bordetella pertussis , hydrolysis , phosphate , periodate , chemistry , hydrochloric acid , biochemistry , microbiology and biotechnology , bacteria , biology , organic chemistry , genetics
Upon hydrolysis with 2 N hydrochloric acid for 2 h, a 3‐deoxy‐octulosonic acid 5‐phosphate was released from the endotoxin of Bordetella pertussis . The structure of the compound was established through chemical degradation. By periodate treatment of the intact endotoxin it was shown that positions 7 and 8 of the bound octulosonic acid phosphate were free, which, if present in a cyclic form, must be a pyranoside.