Open AccessSynthesis of Individual Ribosomal Proteins during a Nutritional Shift‐Up
Author(s) -
Carpenter Graham,
Sells Bruce H.
Publication year - 1974
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1974.tb03464.x
Subject(s) - ribosomal protein , ribosomal rna , eukaryotic large ribosomal subunit , protein biosynthesis , eukaryotic small ribosomal subunit , ribosome , protein subunit , 30s , biology , biochemistry , chemistry , 18s ribosomal rna , rna , gene
Although individual ribosomal proteins are synthesized at the same rate during exponential growth, during a nutritional shift‐up, they are synthesized at different rates. Proteins S6, S10, S14, S20 and L2, L3, L4 and L13 are synthesized to the greatest extent. Proteins S2, S3, S4, S13, S17 and L7, L8, L9, L25, L29 and L30 are synthesized at the lowest rate. Although the average rate of synthesis of 50‐S protein is greater than that for 30‐S protein during a shift‐up, the data on rates of synthesis of individual proteins do not support such a distinction for each individual ribosomal protein. The extent of increased synthesis for the individual ribosomal proteins of the 30‐S subunits correlated well with the assembly order of these proteins. This correlation is not as striking for the 50‐S subunit.