Open AccessThe Biosynthesis of Blood‐Group‐B Character on Human O‐Erythrocytes by a Soluble α‐Galactosyltransferase from Milk
Author(s) -
Pacuszka Tadeusz,
Kościelak Jerzy
Publication year - 1972
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1972.tb02567.x
Subject(s) - galactosyltransferase , enzyme , biosynthesis , character (mathematics) , biochemistry , chemistry , group a , abo blood group system , galactose , human blood , biology , immunology , medicine , physiology , geometry , mathematics
The enzyme α‐galactosyltransferase from human milk catalysed the synthesis of B‐character on blood‐group‐O erythrocytes. Erythrocytes from secretors and nonsecretors participated in this reaction to the same extent. Substances possessing H‐active structure inhibited the acquisition of B‐character by erythrocytes when added to the reaction mixture. The enzyme also incorporated galactose into isolated, water‐soluble substances of erythrocytes with H‐activity from secretors.