Open AccessA Glycopeptide from the Posterior Lobe of Pig Pituitaries
Author(s) -
Holwerda Dirk A.
Publication year - 1972
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1972.tb01918.x
Subject(s) - glycopeptide , threonine , asparagine , fucose , alanine , aspartic acid , biochemistry , arginine , glucosamine , chemistry , serine , peptide , glycan , leucine , amino acid , galactose , glycoprotein , enzyme , antibiotics
An extract from the posterior lobes of pig pituitaries contains a glycopeptide with a molecular mass of 3200 (± 5%). The glycopeptide is present in amounts of the same order as the hormones oxytocin and vasopressin. The peptide portion is composed of seventeen amino acid residues: aspartic acid or asparagine (3), threonine (1), serine (3), proline (1), glycine (2), alanine (3), leucine (3) and arginine (1). The carbohydrate portion, about 55% by weight, is composed of fucose (1), galactose (1), mannose (3) and glucosamine (4). The glycopeptide exhibits none of the known physiological activities of hypophysis except for a slight lipolytic activity.