Open AccessRat Proinsulins and C‐Peptides
Author(s) -
Sundby Finn,
Markussen Jan
Publication year - 1972
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1972.tb01679.x
Subject(s) - peptide , amino acid , chemistry , isolation (microbiology) , biochemistry , peptide sequence , biology , bioinformatics , gene
The two rat proinsulins have been separated and the amino acid compositions determined. Using a method previously described for preparing C‐peptides from ox and pork pancreases, three peptides were isolated from rat pancreases and the amino acid compositions of these peptides determined. Data are presented which strongly indicate that two of these peptides constitute the C‐peptide part of the connecting peptide of the two rat proinsulins.