Open AccessCalcium Binding to Sarcoplasmic Membranes
Author(s) -
Fiehn Walter,
Migala Andrea
Publication year - 1971
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1971.tb01387.x
Subject(s) - calcium , vesicle , membrane , biophysics , calcium atpase , chemistry , sarcoplasm , atpase , plasma membrane ca2+ atpase , biochemistry , endoplasmic reticulum , biology , enzyme , organic chemistry
ATP‐Supported calcium accumulation of sarcoplasmic vesicles is abolished when the vesicles are disrupted or made leaky. The native as well as the leaky sarcoplasmic membranes are characterized by a high intrinsic affinity for calcium which does not depend on ATP. Neither the number of the calcium binding sites nor their affinity for calcium is affected when the membranes are deprived of the phospholipids which are essential for the activity of the transport ATPase.