Open AccessAmino Acid Sequence of a 22‐Residue Section from the Variable Part of Pig Immunoglobulin λ‐Chains
Author(s) -
Franěk F.,
Keil B.,
ŠOrm F.
Publication year - 1969
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1969.tb00756.x
Subject(s) - residue (chemistry) , amino acid , peptide sequence , chemistry , sequence (biology) , stereochemistry , peptide , bence jones protein , biochemistry , antibody , amino acid residue , complete sequence , immunoglobulin light chain , biology , genetics , gene , genome
The section which represents a part of a larger fragment of the variable part of pig immunoglobulin λ‐chains is constituted by two peptides (18 residues and 4 residues) of variable character. These peptides were fractionated and their amino acid sequence determined. At certain positions two to four different amino acids were found. There is a close relation between the found amino acid sequence Ala‐Thr‐Leu‐Thr‐Ile‐Thr‐Gly‐Ala‐Gln‐Ala‐Glu‐Asp‐Glu‐Ala‐Asp‐Tyr‐Phe‐Cys‐Ala‐Leu‐Tyr‐Lys Ala Leu Ala Asn Ser Gly Arg Gly Gly Thr Gly and the amino acid sequence of the corresponding region of human type L Bence‐Jones proteins.