Open AccessEnzymes Involved in Fructose Metabolism in Liver and the Glyceraldehyde Metabolic Crossroads
Author(s) -
Sillero M. A. G.,
Sillero A.,
Sols A.
Publication year - 1969
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1969.tb00696.x
Subject(s) - fructokinase , aldolase a , glyceraldehyde , enzyme , metabolism , fructose bisphosphate aldolase , metabolic pathway , biochemistry , fructose , isozyme , glycolysis , oxidative phosphorylation , biology , chemistry , dehydrogenase
Fructokinase, the B isoenzyme of fructosediphosphate aldolase and triokinase, the three enzymes of the Hers' pathway for fructose metabolism, are constitutive in adult rats. A quantitative model of the metabolic crossroads of d ‐glyceraldehyde has been developed. This model permits a prediction of the relative contributions of the phosphorylative, oxidative and reductive pathways in different conditions. The main pathway for d ‐glyceraldehyde metabolism in liver is phosphorylation by triokinase.