Open AccessThe Stereochemistry of α‐Oxidation of Fatty Acids in Plants
Author(s) -
Hitchcock C.,
Morris L. J.,
James A. T.
Publication year - 1968
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1967.tb19547.x
Subject(s) - palmitic acid , myristic acid , chemistry , pentadecanoic acid , acetone , fatty acid , organic chemistry , stereochemistry , biochemistry
Solutions of pea‐leaf acetone‐dried powder oxidise [1‐ 14 C]palmitic acid to 14 CO 2 , and oxidise [ 14 C 16 ]palmitic acid to 14 CO 2 ]pentadecanoic acid and [ 14 C]myristic acid. If d ‐2‐hydroxy[ 12 C]‐palmitic acid is also present, these metabolites are slightly less radioactive; if l ‐2‐hydroxy[ 12 C]‐palmitic acid is also present, the metabolites are much less radioactive. It is concluded that the sequential α‐oxidation of long‐chain fatty acids involves the l ‐2‐hydroxyacid preferentially, thus: RCH 2 CO 2 H→ l ‐RCHOHCO 2 H→RCO 2 H→ etc.