Open AccessSelfassembly of Defective Particles of the Bacteriophage fr
Author(s) -
Hohn T.
Publication year - 1967
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1111/j.1432-1033.1967.tb00119.x
Subject(s) - rna , bacteriophage , icosahedral symmetry , bacteriophage ms2 , virus , chemistry , biophysics , virology , biology , crystallography , biochemistry , coat protein , escherichia coli , gene
The assembly of protein subunits and RNA of the icosahedral, RNA‐containing bacteriophage fr was studied. Conditions were found under which the constituents could be specially reaggregated to form virus‐like particles, a small fraction of which was infective. The RNA seems to be essential for the assembly process.