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Current incidence and residual risk of HIV, HBV and HCV at Canadian Blood Services
Author(s) -
O’Brien S. F.,
Yi Q.L.,
Fan W.,
Scalia V.,
Fearon M. A.,
Allain J.P.
Publication year - 2012
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.2012.01584.x
Subject(s) - residual risk , incidence (geometry) , medicine , window period , human immunodeficiency virus (hiv) , residual , virology , blood donor , blood donations , demography , immunology , antibody , serology , mathematics , algorithm , sociology , geometry
Estimates of the viral residual risk should be updated to reflect current incidence of infection in blood donors. Incidence rates were estimated for allogeneic whole‐blood donations made to Canadian Blood Services from 2006 to 2009 based on transmissible disease conversions of repeat donations within a 3‐year period. Residual risk was estimated as the incidence multiplied by the window period. The residual risk of HIV was 1 per 8 million donations, HCV 1 per 6·7 million donations and HBV 1 per 1·7 million donations. The residual risk remains low and has decreased for HCV since our previous estimates due to reduced incidence.