Premium
An evaluation of automated blood collection mixers
Author(s) -
Van Der Meer P. F.,
Pietersz R. N.
Publication year - 2006
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.2006.00831.x
Subject(s) - mixing (physics) , chromatography , anticoagulant , blood collection , complete mixing , chemistry , biomedical engineering , materials science , surgery , medicine , emergency medicine , physics , quantum mechanics , mass transfer
Background and Objectives We investigated the mixing capacity of two whole blood (WB) collection mixers. Materials and Methods WB was simulated by using a 25% glycerol solution warmed to 35 °C. Citrate–phosphate–dextrose (CPD) anticoagulant of a collection system was stained with toluidine blue, and simulated WB was added at 30, 60 or 90 ml/min, respectively ( n = 3 per flow speed). The optical density (OD) of 10‐ml fractions was measured, and results are expressed as percentage of a well‐mixed ‘100%‐sample’. Results CompoGuard showed adequate mixing at all three flow speeds (average ODs 96–103%). HemoLight showed good mixing at 60 and 90 ml/min (ODs from 97 to 101%). At 30 ml/min, mixing appeared suboptimal, but still conformed to our requirements with ODs from 96% to 104%. Conclusion Both mixers give sufficient mixing of whole blood with anticoagulant.