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Understanding the Knops Blood Group and its Role in Malaria
Author(s) -
Moulds Joann M.
Publication year - 2002
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.2002.tb05297.x
Subject(s) - transfusion medicine , malaria , immunology , antibody , medicine , disease , blood transfusion , infectious disease (medical specialty) , blood group antigens , intensive care medicine
The antibodies that once were referred to as "HTLAs" have now help to define an entire blood group system with a well characterized genetic basis. Although not "clinically significant" in transfusion medicine, the Knops blood group has gained importance in the field of infectious disease. Its further role in protein (CR1) function and autoimmune diseases remains unknown but may provide interesting work for years to come.