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Analysis of CD34‐Expressing Cells in Clinical Practice
Author(s) -
Serke S.,
Beyer J.,
Rick O.,
Schwella N.,
Meyer O.,
Hildebrandt M.,
Huhn D.
Publication year - 1998
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1998.tb05459.x
Subject(s) - flow cytometry , cd34 , in vitro , clinical practice , haematopoiesis , stem cell , immunology , andrology , biology , medicine , microbiology and biotechnology , biochemistry , family medicine
The flow cytometric determination of haemopoietic cells defined as CD34‐ expressing cells has greatly added to the improvement of the management of harvesting circulating haemopoietic cells for subsequent autologous reinfusion in the setting of high‐dose chemo/(radio)‐therapy. Additionally, this flow cytometric determination has replaced, in some institutions, the in‐vitro culture test for CFU‐GM as the measure to estimate the haemopoietic potential of the cells to be reinfused/transplanted.