Premium
Molecular Genetics of the ABO Histo‐Blood Group System
Author(s) -
Yamamoto Fumiichiro
Publication year - 1995
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1995.tb00339.x
Subject(s) - abo blood group system , genetics , glycosyltransferase , allele , biology , gene , locus (genetics) , coding region
Molecular genetic study of the histo‐blood group ABO system has elucidated the allelic basis of this genetic locus. Comparison of the nucleotide sequence has identified in the coding region differences which change amino acid sequences of the glycosyltransferases coded by these genes. Effects of the differences (mutations) on the specificity and activity of the glycosyltransferases have been examined.