Premium
IMMUNITY IN HEPATITIS C VIRUS INFECTION
Author(s) -
PRINCE ALFRED M.
Publication year - 1994
Publication title -
vox sanguinis
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1994.tb04581.x
Subject(s) - virology , immunity , medicine , immunology , virus , hepatitis virus , hepatitis c virus , hepatitis a virus , hepatitis , immune system
Immunity after HCV infection is weak, even after reinfection with the identical strain of virus. Even chronically infected chimpanzees can be reinfected. Weak immunity may reflect the fact that HCV virions are coated with lipoproteins (VLDL), preventing antibody binding. This phenomenon presents a serious challenge for development of vaccines.