Premium
Rheological Evaluation of X‐Ray Irradiated Blood
Author(s) -
Suzuki Yoji,
Seiyama Akitoshi,
Tateishi Norihiko,
Yamanishi Shigeki,
Maeda Nobuji
Publication year - 1993
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1993.tb05151.x
Subject(s) - irradiation , polyvinyl chloride , rheology , red blood cell , chemistry , blood viscosity , membrane , food science , materials science , biochemistry , medicine , composite material , physics , organic chemistry , nuclear physics
CPD blood, in glass containers and polyvinyl chloride (PVC) bags, was X‐irradiated with 50 Gy (n = 4), and then stored for up to 4 weeks. Rheological, hematological and biochemical changes of the red cells during storage were examined. Changes in blood viscosity and various properties of red cells (deformability, shape, hematological indices and concentrations of 2,3‐diphosphoglycerate and nucleotides) during storage at 4°C were not altered by the irradiation. The rheological, biochemical and morphological properties of red cells were as well preserved in PVC bags as in glass containers. No abnormal and/or cross‐linked proteins in red‐cell membranes were induced by the irradiation. Irradiation of PVC bags did not affect the above properties of red cells through any changes in the bag constituents. In conclusion, X‐ray irradiation with 50 Gy to CPD blood in PVC bags does not affect the rheological functions of red cells.