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Isoagglutinins following ABO‐Incompatible Bone Marrow Transplantation
Author(s) -
Wernet Dorothee,
Mayer Gerhard
Publication year - 1992
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1992.tb01194.x
Subject(s) - abo blood group system , bone marrow transplantation , medicine , bone marrow , transplantation , isoantibodies , immunology , abo incompatibility , transplantation chimera , bone marrow transplant , surgery , antibody , biology , stem cell , haematopoiesis , hematopoietic cell , genetics
Isoagglutinins were investigated following ABO‐incompatible bone marrow transplantation. In major incompatibility anti‐A tends to require more time to disappear than anti‐B. Correspondingly, A erythrocytes require more time to become demonstrable. There is no such difference in major plus minor incompatibility. In minor incompatibility, isoagglutinins against the recipient blood group may be produced early after bone marrow transplantation, which then give way to a possibly lifelong tolerance for the recipient's old blood group.