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Management of a Severe Transfusional Problem in a Patient with Alloantibody to Kpb (K4)
Author(s) -
Kohan A.I.,
Reybaud J.F.,
Salamone H.J.,
Rey J.A.,
Rey C.E.,
Villaravid N.,
Papa S.,
Goldztein S. Cyrulik,
Calahonra R.,
Avalos J.C. Sanchez
Publication year - 1990
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1990.tb00239.x
Subject(s) - medicine
The case of a 58‐year‐old male with severe anemia after hemicolectomy is described. The patient proved to be Kp(b–), and the serum contained anti‐Kp b . Because no Kp(b–) donors were available, two incompatible units are administered after intravenous gammaglobulin (400 mg/kg/day) and hydrocortisone (500 mg). The tolerance was good, without signs of increased red cell destruction. Pending the arrival of compatible blood from the American Red Cross, the hematocrit reached 18%, and the direct antiglobulin test remained negative.