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Thrombocytopenia Following Routine Blood Transfusion: Micro‐Aggregate Blood Filters Prevent Worsening Thrombocytopenia in Patients with Low Platelet Counts
Author(s) -
Lim S.,
Boughton B.J.,
Bareford D.
Publication year - 1989
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1989.tb03046.x
Subject(s) - medicine , platelet , platelet transfusion , blood transfusion , bone marrow , surgery , gastroenterology
. 11 patients with anaemia and thrombocytopenia due to bone marrow failure each received 2 sets of red‐cell transfusions. They were randomised to receive 1 blood transfusion through a standard 170‐μm giving set filter and another through a 40 μm micro‐aggregate filter. After transfusion, the mean fall in platelet count was 15times 10 9 /1 (41.7%) and 1.4times 10 9 /1 (4.6%), respectively (p<0.01). The results confirm the findings of a previous study which showed that micro‐aggregate filters prevent a post‐transfusional decrease in platelet counts. In addition, this new study shows that this is clinically relevant in patients who are thrombocytopenic at the time of their blood transfusion.