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Maternal‐Fetal Immune Relationship: Another Point of View
Author(s) -
Vliet J. Hussonvan,
DruytsVoets E.
Publication year - 1988
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1988.tb05147.x
Subject(s) - fetus , pregnancy , fetal circulation , placental circulation , constant (computer programming) , circulation (fluid dynamics) , obstetrics , immunology , medicine , andrology , placenta , biology , physics , mechanics , computer science , genetics , programming language
. Placental transfer of maternal IgG is known to be an active process resulting in a concentration on the fetal side of the circulation ‐ at the apparent expense of that in the mother ‐ at full term. However, when this apparent decrease in maternal IgG is related to the actual hemodilution occurring in parallel, the total inventory of the mother's IgG appears to be constant throughout pregnancy. Therefore, conclusions regarding the variations in IgG concentrations cannot be drawn without simultaneous information about plasma volume fluctuations.