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LKE Red Cell Antigen and Its Relationship to P 1 and P k : Serological Study of a Large Family
Author(s) -
Bruce M.,
Watt A.,
Gabra G.S.,
Mitchell R.,
Lakhesar D.,
Tippett P.
Publication year - 1988
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1988.tb04704.x
Subject(s) - serology , proband , phenotype , biology , population , microbiology and biotechnology , blood group antigens , antigen , isoantigens , family studies , blood donor , immunology , genetics , antibody , medicine , gene , mutation , environmental health
. The fourth example of human anti‐LKE was identified in the serum of an antenatal patient. Study of the red cells of the proband and her family confirmed the recessive inheritance of the LKE‐ phenotype. The blood groups of the family confirmed that P k expression is greater on cells from LKE‐ members than on those from LKE+ members. In this family, the expression of LKE varied with the P 1 phenotype. LKE‐ individuals occurred with an incidence of 0.0017 in the donor population of the Glasgow and West of Scotland Region.