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Prevalence of ABO Maternal‐Infant Incompatibility in Asians, Blacks, Hispanics and Caucasians
Author(s) -
Toy Pearl T.C.Y.,
Reid Marion E.,
Papenfus Linda,
Yeap Hooi H.,
Black Dennis
Publication year - 1988
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1988.tb03897.x
Subject(s) - abo blood group system , medicine , abo incompatibility , demography , immunology , sociology
. Previous studies suggest that race is a risk factor in ABO hemolytic disease of the newborn (ABO‐HDN). In order to compare the prevalence of ABO‐HDN in Asian, Black, Hispanic and Caucasian infants, we studied 10,611 consecutive births at one hospital over a 6‐year period. Among group A infants born to group O mothers, the prevalence of positive DAT differed among the four groups (p=0.007), and was highest in Asians (50%) and lowest in Caucasians (31%). However, the proportions of infants who required exchange transfusion were not different (p=0.351). Among group B infants born to group O mothers, the prevalence of positive DAT was not different among the four groups (p=0.26) and none of these 166 group B infants with a positive DAT result required exchange transfusion. Our findings suggest that there are small ethnic differences in the prevalence of positive DAT results in group A infants born to group O mothers, but the prevalence of clinical disease which requires exchange transfusion does not differ significantly among Asian, Black, Hispanic and Caucasian infants.