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Application of a Microtitre Plate Antiglobulin Technique to Determine the Incidence of Donors Lacking High Frequency Antigens
Author(s) -
Gale S.A.,
Rowe G.P.,
Northfield F.E.
Publication year - 1988
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1988.tb03894.x
Subject(s) - antigen , antiserum , antibody , incidence (geometry) , medicine , immunology , saline , mathematics , geometry
. Approximately 65,000 random blood donors have been screened by a microtitre low ionic strength saline antiglobulin technique over a 12‐month period. Antisera to high frequency antigens including: Vel, Lu b , k, Kp b , Yt a and Er a were used. Additional sera including: anti‐Lan, ‐Co a , ‐Sc 1 and an antibody to an unidentified high frequency antigen, Mrs C.A., have been used as they became available. This has enabled the approximate frequencies of donors lacking the corresponding antigen, to be calculated.