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Higher ATP Level and Reduced Glucose Consumption of Red Cells Stored in PVC Bags Compared to Glass Bottles
Author(s) -
Hegedüs Edit,
Rácz Zoltdn
Publication year - 1987
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1987.tb04923.x
Subject(s) - food science , red blood cell , chemistry , red cell , blood preservation , plasma glucose , biochemistry , andrology , biology , medicine , endocrinology , diabetes mellitus
. Whole blood stored for 21 days at +4 °C in glass bottles showed a decrease in plasma glucose content of 6.6 m M /1, while blood stored in polyvinylchloride bags had a decrease of only 5.3 m M /1. At the same time, red cell ATP was reduced to 69% in bottles compared to 80% in bags (statistically proved differences). The higher red cell ATP level may explain the increased stability of red cells stored in DEHP‐plasticized blood bags. The reduction in glucose consumption suggested that the decrease of red cell ATP and plasma glucose content may be a result of some unidentified inhibitory effects of DEHP on biochemical processes.