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Allo‐Anti‐Chido in a Ch‐Positive Patient
Author(s) -
Giles Carolyn M.,
Hoffman Mary,
Moulds Marilyn,
Harris Michael,
Dalmasso Augustin
Publication year - 1987
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1987.tb03008.x
Subject(s) - allotype , medicine , phenotype , immune system , antibody , immunology , biology , genetics , gene
. Allo‐anti‐Chido (Ch) was detected in a patient whose red cells typed as Ch+. The C4 allotype of the patient was A4,B2 which associates strongly with the Ch phenotype Ch:1,‐2,3,4,‐5,6. Anti‐Ch2 + Ch5 were the Ch specificities identified. Absence of only Ch2 and Ch5 determinants on the C4B protein allowed this unique immune response to blood transfusion.