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Transmission of Human T Cell Lymphotropic Virus Type I by Blood Transfusion before and after Mass Screening of Sera from Seropositive Donors
Author(s) -
Kamihira Simeru,
Nakasima Sigehiro,
Oyakawa Yukinobu,
Moriuti Yukiyosi,
Ichimaru Michito,
Okuda Hiroto,
Kanamura Machiko,
Oota Takiko
Publication year - 1987
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1987.tb02987.x
Subject(s) - seroconversion , virology , medicine , transmission (telecommunications) , agglutination (biology) , virus , blood transfusion , human t lymphotropic virus , antibody , immunology , serology , electrical engineering , myelopathy , psychiatry , spinal cord , engineering
. The human T cell lymphotropic virus type I (HTLV‐I) is transmitted by blood transfusions that contain cell components as one of the virus transmission modes. We carried out mass screening of sera from seropositive donors by a gelatin particle agglutination test to prevent the spread of HTLV‐I by transfusion. Seroconversion rates were compared before and after screening. The results show a remarkable decrease in the rate of infection from 53.6 to 0.9%. Therefore, it is certain that screening by the agglutination method prevents the spread of HTLV–I transmission in blood transfusions.