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Fetomaternal ABO Incompatibility and Erythroblastosis Fetalis
Author(s) -
Bowman J. M.
Publication year - 1986
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1986.tb04855.x
Subject(s) - abo blood group system , medicine , obstetrics , fetus , abo incompatibility , cord blood , rh blood group system , erythroblastosis fetalis , pregnancy , in utero , gestation , umbilical cord , immunology , gynecology , antibody , biology , genetics
. Ninety‐one of 330 fetuses undergoing intrauterine fetal transfusion (IUT) had sufficient residual fetal red cells in their cord blood samples that their ABO blood groups could be determined. Ten of the 91(11%) were ABO incompatible with their mothers. The degree of Rh disease was severe in all 10. Three were hydropic in utero; 5 had the syndrome of hepatocellular damage; in 6, IUT were required between 22 and 26 weeks gestation. The expected incidence of ABO incompatible pregnancies in which the fetuses required IUT if ABO incompatibility had no effect on severity of Rh disease, is 9.7% versus the 11% observed. ABO incompatibility has no effect on ameliorating severity of erythroblastosis after Rh immunization has developed. ABO incompatibility between mother and father should not be taken into account when making decisions regarding the management of an Rh immunized pregnancy.