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Evaluation of Hemoglobin Screening Methods in Prospective Blood Donors
Author(s) -
Ross D. G.,
Gilfillan A. C.,
Houston D. E.,
Heaton W. A. L.
Publication year - 1986
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1986.tb04850.x
Subject(s) - hemoglobin , sulfate , copper sulfate , cutoff , medicine , screening test , test (biology) , copper , chemistry , biology , pediatrics , paleontology , physics , organic chemistry , quantum mechanics
. This study evaluates the performance characteristics of the copper sulfate screening test in routine bloodmobile operations and compares the performance of the copper sulfate test with that of a miniphotometer method of hemoglobin measurement. The copper sulfate and miniphotometer tests provide equivalent pass/fail classification of male donors with a high sensitivity and total efficiency. For female donors, both test methods show substantially lower sensitivity and total efficiency than for male donors; however, the miniphotometer is significantly more sensitive than the copper sulfate test in identifying eligible female donors. The distribution of donor hemoglobin values relative to cutoff values for acceptance may explain the male‐female differences in screening test performance characteristics.