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Diminishing Morbidity and Mortality of Bone Marrow Transplantation
Author(s) -
Tutschka Peter J.
Publication year - 1986
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1986.tb02014.x
Subject(s) - medicine , bone marrow transplantation , regimen , malignancy , bone marrow , leukemia , toxicity , transplantation , intensive care medicine , bone marrow transplant , disease , surgery
. The reasons for the operational failure of bone marrow transplantation (BMT) are familiar and varied. They are the following: nonmarrow toxicity of the preparative regimen, marrow toxicity of the preparative regimen, acute graft‐versus‐host disease (GVHD), opportunistic infections, especially viral infections and recurrence of hematologic malignancy in the case of transplants for leukemia. This review examines operational failure of BMT and presents measures for its prevention.