Premium
An Lu(a‐b‐) Phenotype Caused by an X‐Linked Recessive Gene
Author(s) -
Norman P.C.,
Tippett P.,
Beal R. W.
Publication year - 1986
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1986.tb00208.x
Subject(s) - phenotype , gene , genetics , suppressor , biology , antigen , microbiology and biotechnology , x linked recessive inheritance , x chromosome
. The family of a male Lu(a‐b‐) propositus whose red cells showed some characteristics of the dominant and some of the recessive type of Lu(a‐b‐) phenotype was studied. The investigation revealed a third genetic background for this rare phenotype, an X‐borne suppressor recessive in effect. The notation proposed is XS1 for the normal gene and XS2 for the suppressor gene which affects the expression of Lutheran and other antigens.