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Delayed Hemolytic Transfusion Reaction Associated with Rh Antibody Anti‐f: First Reported Case
Author(s) -
O'Reilly Robert A.,
Lombard Charles M.,
Azzi Raymond L.
Publication year - 1985
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1985.tb00808.x
Subject(s) - antibody , medicine , hemoglobin , transfusion reaction , rh blood group system , blood transfusion , immunology , red blood cell
A delayed hemolytic transfusion reaction (DHTR) occurring in a 30‐year‐old Caucasian man is described. His blood groups were B, CDe/cDE (R 1 R 2 , f‐) K‐, S‐s+, Fy (a + b‐), and Jk (a + b +). Eight days after receiving two units of packed red blood cells, his urine was strongly positive for hemoglobin; serum‐free hemoglobin was 125 mg/dl. Serum contained a clearly reactive Rh antibody of anti‐f specificity and a weakly reactive anti‐Kell. The DHTR was probably caused by an anti‐f alloantibody appearing as an anamnestic response to transfusion of seemingly compatible, but f‐positive blood.