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Storage of Red Cells in a CPD/SAGM System Using Teruflex® PVC
Author(s) -
Högman Claes F.,
Hedlund Kenneth
Publication year - 1985
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1985.tb00790.x
Subject(s) - buffy coat , hemolysis , andrology , in vitro , chemistry , shelf life , blood preservation , medicine , food science , immunology , biochemistry
. A quadruple plastic bag system made of Teruflex® PVC (Terumo) was tested. Red cells separated from plasma and buffy coat were resuspended in SAGM solution. After storage for 42 days, the 24‐hour posttransfusion autologous survival was 73.3±6.6% (X̄ ± SD), range 61.8–80.7%, n = 10. The shape of the cells was changed so that normal or slightly abnormal morphology was found in 37±7% of the cells after 42 days. Spontaneous in vitro hemolysis was 0.63±0.32% (range 0.28–1.13). A sufficient glucose reserve still remained at the end of storage, but glucose consumption and lactate production were impaired during the last 2 weeks due to the increasing acidity. By extrapolation from other studies it is suggested that 35 days is a more suitable shelf life than 42 days in this system.