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Evaluation of Flatbed Reciprocal Motion Agitators for Resuspension of Stored Platelet Concentrates
Author(s) -
Snyder Edward L.,
Ferri Patricia,
Brown Richard,
Gallup Peggy,
Roberts Stanley
Publication year - 1985
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1985.tb00182.x
Subject(s) - shaker , agitator , centrifugation , polyvinyl chloride , composite material , materials science , plastic bag , chromatography , platelet , chemistry , polyolefin , polyethylene , acoustics , physics , biology , mass transfer , immunology , vibration , layer (electronics)
. We studied the storage characteristics of platelet concentrates prepared in polyolefin (PL‐732) and thin‐film polyvinyl chloride (CLX) plastic bags and stored on a newly designed flatbed reciprocal motion agitator with a 1.5 inch (3.8 cm) lateral movement and an oscillation frequency of 70 cycles/min. We also studied the ability of this device to resuspend the platelet button formed after preparative centrifugation. Results showed that platelet concentrates stored on the 1.5‐inch shaker had storage characteristics equivalent to those reported for the conventional 70 cycles/min, 1‐inch (2.5‐cm) lateral movement flatbed shaker. Due to a more rapid acceleration and deceleration rate, however, the 1.5‐inch shaker resuspended the platelet button formed after preparative centrifugation much more efficiently than did the less dynamic 1‐inch shaker. Furthermore, with either agitator, platelet aggregates in the CLX bag were more readily resuspended than were aggregates in the PL‐732 bag due in part to differences in plastic bag wall elasticity.