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High Frequency of Anti‐A and Anti‐B Haemolysins in Certain Ethnic Groups of Nigeria
Author(s) -
Kulkarni A. G.,
Ibazebe R.,
Fleming A. F.
Publication year - 1985
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1985.tb00143.x
Subject(s) - hemolysin , ethnic group , medicine , blood transfusion , hemolysis , immunology , biology , political science , genetics , gene , virulence , law
Out of 11,480 blood donors, 5,380 (46.9%) belonging to a blood group O were screened for the presence of anti‐A and anti‐B haemolysins. Strong haemolysins (complete lysis of A and/or B cells) were detected in 1,739 (32.3%) of these blood donors. A striking observation was the high frequency of these haemolysins amongst ethnic groups originating from the southern part of Nigeria. Possible causes and consequences during blood transfusion and pregnancy are discussed.