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Anti‐C4 in the Serum of a Transfused C4‐Deficient Patient with Systemic Lupus erythematosus
Author(s) -
Giles Carolyn M.,
Swanson Jane L.
Publication year - 1984
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1984.tb00089.x
Subject(s) - medicine , immunology , lupus erythematosus , systemic lupus erythematosus , intensive care medicine , antibody , disease
A C4‐deficient patient with systemic lupus erythematosus had been transfused on several occasions. His red cells reacted with a proportion of anti‐Rg (Rodgers) and anti‐Ch (Chido) reagents, but this was due to a separable antibody that did not have anti‐Rg or anti‐Ch specificity. Eluates of anti‐Rg and anti‐Ch indicate his red cell phenotype to be Rg–Ch–. Anti‐C4 has been identified in his serum that exhibits neither anti‐Rg nor anti‐Ch specificity, but has similar serological characteristics in reacting with C4‐ and C4d‐coated red cells.