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Hepatitis‐Associated Markers in the American Red Cross Blood Donor Population
Author(s) -
Nath N.,
Pielech M.,
Dodd R.Y.
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb04488.x
Subject(s) - hbsag , antibody , medicine , antigen , hepatitis b , population , immunology , blood donor , hepatitis , virology , hepatitis b virus , virus , environmental health
. A total of 20,643 samples of blood donated to three American Red Cross Blood Service regions were tested for antibodies to hepatitis B core antigen (anti‐HBc) in order to evaluate and understand its significance and implications. All 20,643 samples were non‐reactive for hepatitis B surface antigen (HBsAg) when screened at the regions. Overall, 2.2% of all samples were found to have anti‐HBc, and a total of 16 had anti‐HBc in the absence of antibodies to surface antigen (anti‐HBs) activity. 1 of the 16 samples with anti‐HBc in the absence of anti‐HBs was found to have HBsAg when tested by a sensitive procedural modification of the Ausria II test. Samples with low levels of anti‐HBc activity were significantly more likely to be negative for anti‐HBs.