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Studies on the Retention of Passively Transferred Antibodies in Man
Author(s) -
Shibata Yasuo,
Baba Makoto
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb04126.x
Subject(s) - antibody , radioimmunoassay , titer , catabolism , medicine , immunology , pharmacology , metabolism
. Catabolism of intravenously or intramuscularly administered human immunoglobulin in man was studied by the administration of HBs antibodies at a high titer and analysis with a highly sensitive radioimmunoassay technique. The half‐life in the blood of the antibodies in the aggregate‐reduced antibody preparation administered intravenously was found to be 17.7 days and of those in the antibody preparation administered intramuscularly to be 23.8 days.