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Study of a Family with a Variant M Antigen
Author(s) -
Lawe John E.,
LaRoche Linda L.
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb04108.x
Subject(s) - antibody , blood type (non human) , red cell , autoantibody , red blood cell , antigen , immunology , rh blood group system , medicine , family studies , glycoprotein , abo blood group system , microbiology and biotechnology , biology , genetics
. Anti‐M antibody was found in the serum of a 64‐year‐old woman during a routine pre‐operative screen. Her red cell type was MN but the antibody was shown not to be an autoantibody. Blood tests were run on other members of her family, and it was found that her sister's red cells, also type MN, were not agglutinated by the patient's IgM antibody. Chemical studies are reported on the red cell surface glycoproteins of the patient and 2 family members. This red cell variant is compared with previous reports of Ma and is believed to be a further example of this blood type.