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Autoimmune Thrombocytopenia: Serological Behavior of Platelet Antibodies
Author(s) -
Ribera Anna,
MartinVega Carmen,
Massuet Lluis,
Argelagués Enric,
Tornos Carmen,
Triginer José
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb01941.x
Subject(s) - autoantibody , platelet , immunology , medicine , immune thrombocytopenia , antibody , serology , thrombocytopenic purpura , autoimmune thrombocytopenia , antigen , platelet membrane glycoprotein
. The study of the specificity of platelet autoantibodies has made it possible to expand our knowledge about the immune characterization of idiopathic thrombocytopenic purpura. We report on a study of eluates obtained from 10 patients' platelets with autoimmune thrombocytopenia. They were tested with platelets obtained from healthy donors (Zw a + and Zw a ‐) and with type I Glanzmann platelets. Our results, as those reported by van Leeuwen et al. in 1982, suggest that the autoantibodies recognize one or more antigenic markers probably carried by glycoproteins IIb and IIIa.