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Competition between ABO and Le Gene Specified Enzymes
Author(s) -
Pendu J. Le,
Oriol R.,
Lambert F.,
Dalix A. M.,
Lemieux R. U.
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb01938.x
Subject(s) - saliva , abo blood group system , antigen , radioimmunoassay , microbiology and biotechnology , biology , gene , h antigen , chemistry , immunology , genetics , biochemistry
. One B‐ and two A‐specific radioimmunoassays detected A and B antigenic determinants in saliva of ABH nonsecretors. The A or B antigens found in saliva of nonsecretors had lower efficiency and higher heterogeneity, in the inhibition of the A or B assays, as compared to A or B antigens in saliva of ABH secretors. In the 3 assays, samples of nonsecretor Lewis positive donors (Le a ) had less A or B antigens than samples of nonsecretor Lewis negative donors (Le c ), suggesting that there is a competition between A or B and Le gene‐specified products.