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A New Low‐Frequency Antigen, Hg a (Hughes) 1
Author(s) -
Rowe G. P.,
Hammond W.
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb01920.x
Subject(s) - antigen , antibody , mendelian inheritance , microbiology and biotechnology , medicine , genetics , immunology , biology , gene
. This paper describes a ‘new’ low‐frequency antigen, Hg a which came to light during routine antibody identification tests. 3 families were investigated, 2 found during the screening of 5,434 random group 0 donors, giving a frequency of 1:2717. The families showed the antigen to be inherited as a Mendelian autosomal dominant character segregating independently of: Rh, MNS and is not linked to X or Y. No pure examples of the corresponding antibody have been discovered in testing 6,580 sera from normal donors in South Wales.