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Cytomegalovirus (CMV) Antibody in Male Homosexuals: A Source for CMV Immune Globulin
Author(s) -
Ikram H.,
Prince A.M.,
Baker L.N.
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb01881.x
Subject(s) - cytomegalovirus , immunology , antibody , virology , complement fixation test , titer , population , immune system , globulin , biology , medicine , virus , herpesviridae , viral disease , serology , environmental health
. Male homosexuals have been found to have an extraordinarily high prevalence, and high titers, of antibodies to cytomegalovirus (CMV), as determined by complement‐fixation and passive hemagglutination tests. These findings support other data suggesting that CMV may be sexually transmitted. The high titers of CMV antibody found in this population suggest that the homosexual population may be a valuable source of plasma for preparations of CMV immune globulins. CMV immune globulins may be useful in passive immunoprophylaxis or immunotherapy in immunosuppressed patients.