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Pilot Study for Large‐Scale Plasma Procurement Using Automated Plasmapheresis
Author(s) -
Robinson Angela E.,
Penny Alan F.,
Smith James,
Tovey Derrick L.
Publication year - 1983
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1983.tb01876.x
Subject(s) - plasmapheresis , procurement , scale (ratio) , medicine , operations management , business , engineering , immunology , geography , marketing , antibody , cartography
. A pilot study for large‐scale automated plasmapheresis using the Haemonetics Model 50 machine was undertaken in the Yorkshire Region of the United Kingdom to determine the viability of such a programme for national self‐sufficiency in fresh plasma procurement for factor VIII concentrate production. The study was designed to resolve three areas of concern: donor safety and recruitment; a cost analysis, and the choice of anticoagulant for optimum factor VIII yields. The results show that large‐scale automated plasmapheresis could safely and economically produce high‐quality source plasma necessary for national self‐sufficiency.