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Survival of Homozygous Co a (Colton) Red Cells in a Patient with Anti‐Co a 1
Author(s) -
Kurtz S.R.,
Kuszaj T.,
Ouellet R.,
Valeri C.R.
Publication year - 1982
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1982.tb01113.x
Subject(s) - incubation , red cell , titer , antibody , microbiology and biotechnology , in vivo , chemistry , medicine , immunology , biology , biochemistry , genetics
The in vivo survival of Co(a+b‐) red cells in a patient with anti‐Co a was studied using a small aliquot of 51 Cr‐labeled red cells. The antibody reacted at room temperature without incubation and after completion of the antihuman globulin test with both reactions enhanced by ficin. Circulation of transfused cells was shortened with a T 50 of 5 min. The patient's anti‐Co a titer rose following transfusion to 1:256. These data suggest that individuals with anti‐Co a should receive Co(a‐b+) red cells for transfusion.