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Two New Slow‐Moving Variants of Human Serum Albumin
Author(s) -
Nishimukai Hiroaki,
Kera Yoshio,
Sano Yuji,
Sakata Kiyoshi,
Kitamura Hajime,
Tsukamoto Kosuke,
Yamasawa Kichihei
Publication year - 1982
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1982.tb01105.x
Subject(s) - albumin , serum albumin , genetics , inheritance (genetic algorithm) , trait , biology , gene , biochemistry , computer science , programming language
Two new slow‐moving variants of human serum albumin were found in members of two unrelated Japanese families. These variants, different from each other and from the slow‐moving variants described previously, were designated albumin ‘Okinoerabu’ and albumin ‘Akasaka’. The mode of inheritance of each variant was consistent with an autosomal codominant trait. A very rare type, homozygote for a variant, albumin ‘Okinoerabu’, was also detected. The segregation data of albumin and Gc showed no discrepancy from the postulation of a linkage between these two loci.