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Immunological Monitoring of a Patient with Guillain‐Barré Syndrome Successfully Treated with Plasma Exchange
Author(s) -
Fiorini G.,
Bigi G.,
Paracchini M. L.,
Marinig C.,
Gibelli A.
Publication year - 1982
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1982.tb01103.x
Subject(s) - guillain barre syndrome , medicine , peripheral , immunology , peripheral blood , lymphocyte
A patient with Guillain‐Barré syndrome was successfully treated by plasma exchange (without any other therapy), and the relationship between changes in his peripheral blood lymphocyte subpopulations and the clinical improvement induced by plasma‐pheresis was studied. At the recovery, the most interesting findings were an increase in T suppressor lymphocytes, and in Fc receptor‐bearing lymphocytes (above normal values), together with a decrease in B lymphocytes. In this patient, plasma exchange not only removed toxic humoral factors, but also restored a normal balance among peripheral lymphocytes.