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Automation of Cross‐Matching and Red Cell Antibody Screening
Author(s) -
Wattar B.,
Lambermont M.,
Govaerts A.
Publication year - 1982
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1982.tb01092.x
Subject(s) - antibody , red cell , automation , matching (statistics) , medicine , red blood cell , computational biology , computer science , immunology , biology , engineering , pathology , mechanical engineering
. This automatic system combines the major cross‐match with screening for allo and autoantibodies. Moreover, the detected antibodies can be identified on a panel of frozen and thawed red blood cells (RBC). The system is made up of two connected samplers, three channels working, respectively, with bromelin PVP, LISP and saline PVP at 4°C, three colorimeters or three red cell autocounters and their recorders. The optimal speed is 50 sample/h and one whole test requires 19 min. Our experience indicates that this automatic system is appreciably more sensitive and much more rapid and efficient than manual techniques. In spite of increased sensitivity, the ratio of rejected bags does not exceed 2.7%.