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Observations on the Anton Antigen and Antibody
Author(s) -
Poole Joyce,
Giles Carolyn M.
Publication year - 1982
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1982.tb00015.x
Subject(s) - antibody , antigen , antiserum , phenotype , microbiology and biotechnology , biology , locus (genetics) , proteolytic enzymes , blood group antigens , gene , enzyme , immunology , genetics , biochemistry
Five antisera with Anton specificity were studied serologically. The determinant is not sensitive to treatment by proteolytic enzymes (notably trypsin) and is present on cells of the recessive type of Lu(a‐b‐) phenotype. The Anton ‘para‐Lutheran’ antigen/antibody therefore seems to be associated with the Lutheran blood group system only by means of cells of the dominant type of the Lu(a‐b‐) phenotype which is controlled by In(Lu) , a gene independent of the Lutheran locus.