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The Lud Cold Agglutinin: A Further Antibody Recognizing N‐Acetylneuraminic Acid‐Determined Antigens not Fully Expressed at Birth
Author(s) -
Roelcke D.
Publication year - 1981
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1981.tb01056.x
Subject(s) - cold agglutinin , antibody , antigen , proteases , agglutinin , isoantibodies , n acetylneuraminic acid , biology , immunology , sialic acid , biochemistry , enzyme , lectin
From a patient, a new type of human cold agglutinin, Lud, which reacts with a determinant involving N‐acetylneuraminic acid and which is not fully expressed at birth, is described. This antibody differs from a recently described cold agglutinin, Fl. The antigenic determinant recognized by antibody Lud is diminished after treatment of erythrocytes with proteases, whereas that recognized by Fl is not.